Effectiveness of Lom-Jub-Pong-Hang-Kao Nano-emulsion GelsContaining Combination and Single Drugs in Treatment of Osteoarthritis Symptoms
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Abstract
The purpose of this research was to compare the effectiveness of Lom-Jub-Pong-Hang-Kao nano-emulsion gels containing combination and single drugs in the treatment of osteoarthritis symptoms. In comparing 2 groups, randomly assigned groups, results were measured before and after the experiment within group and between groups. Fifteen nano-emulsion gels were divided into the combination group, while another fifteen nano-emulsion gels were allocated to the single drug group. The data collected were personal information, VRS, swelling, degree of movement and Thai modified WOMAC. Content validity was 1.00. The instrument's reliability was assessed by calculating the Pearson correlation coefficient, which ranged between 0.80 and 1.00. Personal information were analyzed using descriptive statistics and comparative analysis of variable differences within the group and between groups using Wilcoxon Signed Ranks Test and Mann-Whitney U Test. This research found that after the treatment, both groups experienced a statistically significant decrease in pain scores, degrees of movement, and severity levels. However, the reduction in swelling was not statistically significant for either group. Comparing between the groups, both the combination and single drug groups showed no statistically significant differences in pain scores, swelling, degree of movement, or severity levels. In summary, both treatment approaches were equally effective.
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